Seminars


For further information on any CSM events please e-mail: csm@lshtm.ac.uk.


Centre for Statistical Methodology Seminar
Survival Analysis and Statistical Computing Themes
Friday 31 March 2017, 12:45-2:00pm
LG9, Keppel Street
Multistate survival analysis in Stata
Michael Crowther (University of Leicester)

Abstract: Multi-state models are increasingly being used to model complex disease profiles. By modelling transitions between disease states, accounting for competing events at each transition, we can gain a much richer understanding of patient trajectories and how risk factors impact over the entire disease pathway. In this talk, I will introduce some new Stata commands for the analysis of multi-state survival data. This includes msset, a data preparation tool that converts a dataset from wide (one observation per subject, multiple time and status variables) to long (one observation for each transition for which a subject is at risk for). I develop a new estimation command, stms, that allows the user to fit different parametric distributions for different transitions, simultaneously, while allowing for sharing of covariate effects across transitions. Finally, predictms calculates transition probabilities, and many other useful measures of absolute risk, following the fit of any model using streg, stms, or stcox, using either a simulation approach or the Aalen–Johansen estimator. Importantly, predictms also allows different parametric distributions to be specified for different transitions, passed as model objects. I illustrate the software using a dataset of patients with primary breast cancer.

Centre for Statistical Methodology Seminar
Friday 28 April 2017, 12:45-2:00pm
LG9, Keppel Street
Title TBC
Nuno Sepulveda (LSHTM)

Centre for Statistical Methodology Seminar
Friday 26 May 2017, 12:45-2:00pm
LG9, Keppel Street
Title TBC
Suzie Cro (Imperial College London)

Centre for Statistical Methodology Seminar
Friday 30 June 2017, 12:45-2:00pm
LG9, Keppel Street
Title TBC
Rebecca Walwyn (University of Leeds)