Seminar slides

Centre for Statistical Methodology Seminar
Design and Analysis for Dependent Data Theme
26 September 2014
Modelling repeated measures growth data by aligning significant growth events and modelling changes in within-individual variability over time
Prof Harvey Goldstein (University of Bristol)
Slides (.pdf, 0.8MB)

Centre for Statistical Methodology Seminar
Analysis of Clinical Trials Theme
25 July 2014
Identifying relevant sensitivity analyses for clinical trials
Tim Morris (MRC Clinical Trials Unit)
Slides (.pdf, 0.2MB)

PATHWAYS Event
Causal Mediation Analysis in Social and Medical Research
St. Catherine’s College, Oxford
7 July 2014
Evidence and causality in the social and medical sciences
(Federica Russo, Universita’ degli Studi di Ferrara) Slides (2.1MB)
Modern mediation methods in the social sciences (David Mackinnon, Arizona State University) Slides (0.6MB)
Mediational analysis in psychotherapeutic trials: change and error (Andrew Pickles, Institute of Psychiatry)
Mediation analysis in the political and economic sciences (Luke Keele, Penn State University) Slides (0.5MB)
Mediation analysis with multiple mediators (Bianca De Stavola, LSHTM) Slides (2.4MB)

Centre for Statistical Methodology Seminar
Design and Analysis of Observational Studies Theme
27 June 2014
Cross-national differences in older adults physical functioning: results from HRS, ELSA and SHARE studies of ageing
Omar Paccagnella (University of Padova)
Slides (.pdf, 0.7MB)

Centre for Statistical Methodology Seminar
Design and Analysis of Observational Studies Theme
20 June 2014
Nested case-control studies: Should one break the matching?
Ørnulf Borgan (University of Oslo)
Slides (.pdf, 0.3MB)

Centre for Statistical Methodology Seminar
Causal Inference Theme
16 May 2014
SMART studies and the personalization of medical care
Erica Moodie (McGill University)
Slides
(.pdf, 0.6MB)

Centre for Statistical Methodology Seminar
Meta-analysis and Systematic Reviews Theme
31 January 2014
Network meta-analysis
Ian White (MRC Biostatistics Unit)
Slides (.pdf, 1.3MB)

Centre for Statistical Methodology Seminar
Causal Analysis Theme
17 January 2014
Mechanisms and the evidence hierarchy
Federica Russo (University of Ferrara, Italy)
Slides (.pdf, 1.7MB)

LSHTM Inaugural Lecture
4 December 2013
Hygienic thinking and exotic methods
Bianca De Stavola (LSHTM)
Slides (.pdf, 10.0MB)

Centre for Statistical Methodology Seminar
Survival Analysis Theme
2 December 2013
Using relapses information to predict the risk of death for breast cancer patients: dynamic prediction and validation in UK population
Virginie Rondeau & Audrey Mauguen (INSERM, Bordeaux, France)
Slides (.pdf, 0.5MB)

Centre for Statistical Methodology Seminar
Health Economic Evaluation Theme
29 November 2013
The Regression Discontinuity Design in epidemiology: an application to the prescription of statins
Gianluca Baio (UCL)
Slides (.pdf, 2.3MB)

Centre for Statistical Methodology Seminar
Statistical Computing Theme
25 October 2013
The importance of computing in statistical analysis: examples from two R packages
Antonio Gasparrini (LSHTM)
Slides (.pdf, 0.5MB)

Centre for Statistical Methodology Seminar
Missing Data Theme
28 June 2013
Improving upon complete case analysis when covariates are missing not at random
Jonathan Bartlett (LSHTM)
Slides (.pdf, 0.4MB)

Centre for Statistical Methodology Seminar
Pharmaco-epidemiology Theme
13 May 2013
Hierarchies of Evidence

Sir Michael Rawlins (President of the Royal Society of Medicine)
Slides (.pdf, 2.1MB)

Centre for Statistical Methodology Seminar
Health Economic Evaluation Theme
26 April 2013
A comparison of direct and indirect methods for the estimation of health utilities from clinical outcomes
Monica Hernandez (University of Sheffield)
Slides (.pdf, 0.4MB)

Centre for Statistical Methodology Seminar
Pharmaco-epidemiology Theme
19 March 2013
Fighting a battle up Hill’s: Discovering new roles for observational healthcare data in causality assessment

Jesse Berlin (VP, Epidemiology, Janssen Research & Development)
Slides (.pdf, 1.9MB)

Centre for Statistical Methodology and British and Irish Region of the International Biometric Society Scientific Meeting
40+ Years of the Cox Model
8 March 2013
The Cox model: Introduction and history
Bianca De Stavola (LSHTM)
Slides (.pdf, 1.1MB)

Centre for Statistical Methodology Seminar
Health Economic Evaluation Theme
22 February 2013
Methods for estimating survival benefits in the presence of treatment crossover: a simulation study
Nick Latimer (University of Sheffield)
Slides (.pdf, 1.5MB)

Centre for Statistical Methodology Seminar
Health Economic Evaluation & Causal Inference Themes
31 January 2013
Evaluating treatment effectiveness under model misspecification: a comparison of targeted maximum likelihood estimation with bias-corrected matching

Noemi Kreif (LSHTM)
Slides (.pdf, 0.7MB)

Centre for Statistical Methodology Seminar
Survival Analysis Theme
25 January 2013
Missing data and composite endpoints: efficient estimation of the distribution of time to composite endpoint when one of the endpoints is incompletely observed
Rhian Daniel (LSHTM)
Slides (.pdf, 1.9MB)

Centre for Statistical Methodology Seminar
Design and Analysis of Dependent Data Theme
30 November 2012
Relating changes in two variables using bivariate multilevel spline models
Corrie Macdonald-Wallis (University of Bristol)
Slides (.pdf, 0.5MB)

Centre for Statistical Methodology Autumn Educational Seminar Series
29 November 2012
Systematic reviews and meta-analysis (meta-analysis)
Bianca De Stavola and Tim Collier (LSHTM)
Slides (.pdf, 0.8MB)

Centre for Statistical Methodology Autumn Educational Seminar Series
27 November 2012
Systematic reviews and meta-analysis (systematic reviews)
Alma Adler (LSHTM)
Slides (.pdf, 0.2MB)

Centre for Statistical Methodology Autumn Educational Seminar Series
22 November 2012
Missing data (intermediate)
Mike Kenward (LSHTM)
Slides (.pdf, 0.2MB)

Centre for Statistical Methodology Autumn Educational Seminar Series
20 November 2012
Missing data (basic)
James Carpenter (LSHTM)
Slides (.pdf, 0.4MB)

Centre for Statistical Methodology Seminar
Analysis of Count Data Theme
16 November 2012
What’s an outlier in long-tailed discrete data?
Dr Mario Cortina Borja (UCL Institute of Child Health)
Slides (.pdf, 1.2MB)

Centre for Statistical Methodology Autumn Educational Seminar Series
15 November 2012
Agreement, reliability and repeatability studies (categorical)
Jonathan Bartlett (LSHTM)
Slides (.pdf, 0.1MB)

Centre for Statistical Methodology Autumn Educational Seminar Series
13 November 2012
Agreement, reliability and repeatability studies (continuous)
Jonathan Bartlett (LSHTM)
Slides (.pdf, 0.2MB)

Centre for Statistical Methodology Seminar
Causal Inference Theme
5 October 2012
Trial designs fully integrating biomarker information for the evaluation of treatment-effect mechanisms in personalised (stratified) medicine
Dr Richard Emsley (University of Manchester)
Slides (.pdf, 0.4MB)

Centre for Statistical Methodology Seminar
Meta-analysis and Systematic Reviews Theme
28 September 2012
Empirical evidence on sources of bias in randomised controlled trials: methods of and results from the BRANDO study
Prof Jonathan Sterne (University of Bristol)
Slides (.pdf, 0.8MB)

Centre for Statistical Methodology Seminar
Causal Inference & Health Economic Evaluation Themes
3 July 2012
An application of targeted maximum likelihood estimation to health economic evaluation
Dr Susan Gruber (Harvard School of Public Health)
Slides (.pdf, 0.8MB)

Centre for Statistical Methodology Seminar
25 May 2012
Modelling of time dependencies in associations between health effects and protracted exposures
Dr Antonio Gasparrini (LSHTM)
Slides (.pdf, 0.8MB)

3rd UK Mplus Users Meeting
LSHTM
24 May 2012
Mediation analysis with SEM or causal inference: Where is the difference? (Bianca De Stavola, LSHTM) Slides (.pdf, 0.6MB)
Process evaluation and causal mediation analysis using Mplus (Richard Emsley, University of Manchester) Slides (.pdf, 0.5MB)
Lifelong socioeconomic position and biomarkers of later life health (George Ploubidis, LSHTM)
CACE – Complier-average Causal Effects using Mplus: theoretical and practical issues (Hugo Cogo-Moreira, Federal University of Sao Paulo) Slides (.pdf, 0.1MB)
Alcohol-related dysfunction in working-age men in Izhevsk, Russia: An application of Structural Equation Models to study the association with education (Sarah Cook, LSHTM)
Math anxiety precedes math helplessness: Via logical comprehension and self efficacy to math performance (Jan Zirk-Sadowski, University of Cambridge)
Developmental paths and constrained trajectories (Andrew Pickles, Institute of Psychiatry, King’s College London) Slides (.pdf, 0.7MB)
Physical activity and blood pressure, models and methods to examine their association in mid life (Graciela Muniz, MRC Unit for Lifelong Health and Ageing, University College London)
Lies, damned lies and latent classes: Can factor mixture models allow us to identify the latent structure of common mental disorders? (Rachel McCrea, University College London) Slides (.pdf, 0.1MB)
Disordered eating patterns in adolescence: Using ESEM for validation (Nadia Micali, Institute of Psychiatry, King’s College London)
General random effect latent variable modelling: Subjects, items, contexts and parameters (Tihomir Asparouhov, Mplus) Slides (.pdf, 0.4MB)

Centre for Statistical Methodology Seminar
Design and Analysis of Observational Studies Theme
27 April 2012
Why we should all be Bayesians (and often are without realising it)
Prof Neil Pearce (LSHTM)
Slides (.pdf, 1.5MB)
Audio (.mp3, 29.5MB)

International Biometric Society – British and Irish Region (IBS-BIR) Spring Meeting and LSHTM Centre for Statistical Methodology Meeting
29 March 2012
Model selection for genetic and epidemiological data
Stijn Vansteelandt (Ghent University and LSHTM), Christian Robert (Universite Paris Dauphine), Doug Speed (University College London), David Clayton (University of Cambridge)
Slides and audio (.m4v)
Audio (.mp3)

Centre for Statistical Methodology Seminar
Design and Analysis of Observational Studies Theme
12 April 2012
Causal inference in observational settings in social research
Prof Peter Davis (University of Auckland)
Slides (.pdf, 1.7MB)

Centre for Statistical Methodology Seminar
Time Series Theme
23 February 2012
Time series regression: advancements in this new tool for epidemiological analyses
Antonio Gasparrini and Ben Armstrong (LSHTM)
Slides – Part I (.pdf, 1.1MB)
Slides – Part II (.pdf, 0.7MB)

Centre for Statistical Methodology Seminar
Causal Inference Theme
23 January 2012
Can counterfactual theory be a complete theory of causality as we practice it in Epidemiology?
Prof Jan VandenBroucke (Leiden University Medical Centre, Netherlands)
Slides (.pdf, 0.2MB)
Slides and audio (apologies for the poor sound quality)
See also D.R. Cox and N. Wermuth. Causality: a Statistical View. International Statistical Review (2004); 72: 285-305.

Department of Medical Statistics Seminar
2 November 2011
Statistical Models for Censored Point Processes with Cure Rates
Dr Jennifer Rogers (LSHTM)
Slides (.pdf, 0.7MB)

Centre for Statistical Methodology Forum
14 October 2011
Correcting for covariate measurement error using regression calibration (Jonathan Bartlett) Slides (.pdf, 0.2MB)
R software: advantages and opportunities (Antonio Gasparrini) Slides (.pdf, 1.9MB)
Statistical methods for causal inference (Rhian Daniel) Slides (.pdf, 0.7MB)

Centre for Statistical Methodology Workshop
Causal Inference Theme
23 September & 6 October 2011
Confounded about confounding? How ‘modern’ causal thinking brings fresh clarity to old concerns
Dr Rhian Daniel & Prof Bianca De Stavola (LSHTM)
Slides (.pdf, 1.1MB)

Centre for Statistical Methodology Seminar
18 August 2011
Evidence Synthesis: Much More than Statistics
Prof Sander Greenland (UCLA)
Audio (.mp3)
Slides and audio (.m4v)

Department of Medical Statistics Seminar
22 July 2011
Good Confidence Intervals for Categorical Data Analyses
Prof Alan Agresti (University of Florida)
Slides (.pdf, 0.3MB)

Centre for Statistical Methodology Seminar & Discussion
Design and Analysis of Observational Studies Theme
27 May 2011
What does the odds ratio estimate in a case-control study?
Prof Neil Pearce (LSHTM)
Slides (.pdf, 0.4MB)
Audio (.mp3, 13.3MB)
For more information see Professor Pearce’s 1993 IJE paper or Professor Laura Rodrigues’s 1990 IJE paper.

Centre for Statistical Methodology Launch
7 April 2011
Some current and potential issues for medical statistics
Prof Sir David Cox (University of Oxford)
Slides and audio (.m4b; 18.8MB)
Audio only
(.mp3; 28.1MB)

Department of Medical Statistics Seminar
23 February 2011
Familial and socio-economic influences on foetal growth across three generations: the Uppsala Birth Cohort Multigenerational Study, Sweden, 1915-2002
Dr Bianca De Stavola (LSHTM)
Slides (.pdf, 1.0MB)

Centre for Statistical Methodology Pre-Launch Meeting
29 September 2010
Time series analysis: from econometrics to epidemiology (Antonio Gasparrini) Slides (.pdf, 1.1MB)
When it comes to data reduction, latent variables are better than PCA! (George Ploubidis) Slides (.pdf, 0.2MB)
Why we shouldn’t ignore measurement error and missingness in our data (Jonathan Bartlett) Slides (.pdf, 0.2MB)
Why causality is not such an impossible word (Rhian Daniel) Slides (.pdf, 0.4MB)

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